How AI is applied across API Evangelist and APIs.io. Read my AI disclosure →
API Evangelist API Evangelist
Discovery
Learnings
Guidance
Toolbox
Alignment
API Evangelist LLC
Discovery
Learnings
Guidance
Toolbox
Alignment
API Evangelist LLC

Need help?

Contact us
Reactome

Reactome interactors API

Molecule interactors

Documentation Provider Profile APIs.io OpenAPI GitHub

Reactome interactors API is one of 23 APIs that Reactome publishes on the APIs.io network, described by a machine-readable OpenAPI specification.

Tagged areas include interactors. The published artifact set on APIs.io includes an OpenAPI specification and API documentation.

This API exposes 16 operations across 16 paths, and defines 8 schemas. It is described by OpenAPI 3.2.0, at version 2.0.

Requests are made against a single base URL, /AnalysisService.

16 operations 16 paths 8 schemas 7 GET9 POST

Metadata

The identity and technical contract details declared by the specification.

Specification
OpenAPI 3.2.0
API Version
2.0
Base URL
https://reactome.org/ContentService
Contact
Reactome
License
Creative Commons Attribution 3.0 Unsupported License
Terms of Service
View terms
Resource Areas
1

Paths & Operations 16

Across 16 paths, the API surfaces 16 operations — 7 GET, 9 POST. Each is listed below with its method, path, parameters, and response codes.

interactors 16

Molecule interactors

GET
/interactors/psicquic/molecule/{resource}/{acc}/details
Retrieve clustered interaction, sorted by score, of a given accession by resource.
getProteinDetailsByResource 4 params → 406500
GET
/interactors/psicquic/molecule/{resource}/{acc}/summary
Retrieve a summary of a given accession by resource
getProteinSummaryByResource 4 params → 406500
POST
/interactors/psicquic/molecules/{resource}/details
Retrieve clustered interaction, sorted by score, of a given accession(s) by resource.
getProteinsDetailsByResource 3 params body → 406500
POST
/interactors/psicquic/molecules/{resource}/summary
Retrieve a summary of a given accession list by resource.
getProteinsSummaryByResource 3 params body → 406500
GET
/interactors/psicquic/resources
Retrieve a list of all Psicquic Registries services
getResources 2 params → 406500
GET
/interactors/static/molecule/enhanced/{acc}/details
Retrieve a custom interaction information of a given accession in Reactome knowledgebase for UI to use, including Reactome entity number
getCustomInteractionsByAcc 3 params → 404406500
GET
/interactors/static/molecule/{acc}/details
Retrieve a detailed interaction information of a given accession
getProteinDetailsByAcc 5 params → 404406500
GET
/interactors/static/molecule/{acc}/pathways
Retrieve a list of lower level pathways where the interacting molecules can be found
getLowerLevelPathways 5 params → 404406500
GET
/interactors/static/molecule/{acc}/summary
Retrieve a summary of a given accession
getProteinSummaryByAcc 3 params → 404406500
POST
/interactors/static/molecules/details
Retrieve a detailed interaction information of a given accession
getProteinsDetailsByAccs 4 params body → 404406500
POST
/interactors/static/molecules/summary
Retrieve a summary of a given accession list
getProteinsSummaryByAccs 2 params body → 404406500
POST
/interactors/token/{token}
Retrieve custom interactions associated with a token
getInteractors 3 params body → 404406500
POST
/interactors/upload/psicquic/url
Registry custom PSICQUIC resource
registryPsicquicURL 3 params body → 400406500
POST
/interactors/upload/tuple/content
Paste file content and get a summary associated with a token
postFileContent 3 params body → 400406413415422500
POST
/interactors/upload/tuple/form
Parse file and retrieve a summary associated with a token
postFile 3 params body → 400406413415422500
POST
/interactors/upload/tuple/url
Send file via URL and get a summary associated with a token
postUrl 3 params body → 400406415422431500

Schemas 8

The contract defines 8 schemas that model the data the API accepts and returns. The most detailed are CustomInteraction (12 properties), Interactor (7 properties), Summary (5 properties), PsicquicResource (4 properties). Each schema is shown below with its type and property counts.

PsicquicResource
object
4 properties
Summary
object
5 properties
CustomInteraction
object
12 properties
Interactors
object
2 properties
TupleResult
object
2 properties
CustomPsicquicResource
object
1 property
Interactor
object
List of Interactors that interacts with the given accession.
7 properties
InteractorEntity
object
This is the list of entities which have been requested.
3 properties

Specification

The full machine-readable OpenAPI contract behind this narrative.

Source

reactome-interactors-api-openapi.yml Raw ↑

Other APIs Reactome publishes across the network.

Reactome database API
AE Profile APIs.io
Reactome discover API
AE Profile APIs.io
Reactome diseases API
AE Profile APIs.io
Reactome download API
AE Profile APIs.io
Reactome entities API
AE Profile APIs.io
Reactome events API
AE Profile APIs.io
Reactome exporter API
AE Profile APIs.io
Reactome identifier API
AE Profile APIs.io
Reactome identifiers API
AE Profile APIs.io
Reactome import API
AE Profile APIs.io
Reactome mapping API
AE Profile APIs.io
Reactome orthology API
AE Profile APIs.io
#interactors
← Back to R APIs
API Details
ID
reactome:reactome-interactors-api
Base URL
https://reactome.org/ContentService
Docs
https://reactome.org/dev/content-service
Provider
Reactome
APIs.io →  GitHub →
Explore more
All APIs Providers APIs.io Network
Work with this as data

Every API here is available over the API and to AI agents over MCP. APIs is not yet its own endpoint on the v1 API. Reach this content through network search and the tag graph, or the MCP server below.

Installs https://mcp.apievangelist.com/mcp in Claude, Cursor, VS Code and the rest — one button, every client.

MCP tools for apis
4 tools reach this content
  • search_api_evangelistSearch every content type across the network at once.
  • find_relatedThe shared-tag relevance graph — what else covers this.
  • get_tagEverything one tag labels, across all content types.
  • guide_topicPRO — a curated bundle for a topic: area, guidance, rules, papers, stories, services.
All tools & prompts
Call it yourself
curl for this page
Search the network for this 
curl "https://api.apievangelist.com/v1/search?q=reactome-interactors-api&limit=10"
Everything under a tag 
curl "https://api.apievangelist.com/v1/tags/reactome-interactors-api"

Discovery needs no key. Full bodies and the synthesis endpoints are Pro.

Get an API key

Free tier, no email required. Sign in with whichever identity you already have.

GitHub Google LinkedIn

A second provider on the same verified email joins the account you already have. Your account

Where this information came from

This is an independent, third-party profile of Reactome interactors API, published by API Evangelist. We do not operate, host, resell, or support these APIs, and we are not affiliated with or endorsed by the company unless stated above. Everything here is built from publicly available information — the company's own site, developer portal, documentation, public repositories, and the specifications it publishes for public use. Nothing is obtained by breaching a system, defeating an access control, or using credentials.

The Kin Score and Agent Readiness rating are independently calculated assessments of a company's public API artifacts, scored against a published rubric. They are not certifications, endorsements, security assessments, or audits.

Corrections, re-scores, and removal are free — no partnership or purchase required, and you do not need to justify the request. A removed company is recorded as unrated, never scored zero for having asked. Acknowledgement within one business day; removal within two.

info@apievangelist.com · Read the full data-sourcing policy →
On a security or compliance team? Put security in the subject line and you will get a person, not a form — we will tell you exactly which public URLs this profile was built from.