NCI SEER API
RESTful API for the Surveillance, Epidemiology, and End Results (SEER) Program. Supports SEER datasets plus staging APIs for cancer staging (TNM and Collaborative Stage algorithms), enabling developers to embed authoritative incidence, survival, and staging logic into their own systems.
NCI SEER API is one of 15 APIs that Cancer.gov publishes on the APIs.io network, described by a machine-readable OpenAPI specification.
Tagged areas include Surveillance, Epidemiology, Staging, and SEER. The published artifact set on APIs.io includes API documentation, an OpenAPI specification, rate-limit docs, and an API reference.
This API exposes 106 operations across 93 paths, organized into 10 resource areas, and defines 67 schemas. It is described by OpenAPI 3.1.0, at version 1.0.
Requests are made against a single base URL, https://api.seer.cancer.gov.
Metadata
The identity and technical contract details declared by the specification.
Authentication & Security 1
NCI SEER API declares
1 security scheme
for authenticating requests.
An API key is passed in the header as X-SEERAPI-Key (apiKeyScheme).
By default, every request must be authenticated.
Paths & Operations 106
Across 93 paths, the API surfaces 106 operations — 11 DELETE, 53 GET, 30 POST, 12 PUT. They span 10 resource areas: staging, rx, ndc, hcpcs, glossary, disease, mph, surgery, recode, naaccr. Each is listed below with its method, path, parameters, and response codes.
Staging Algorithms
Antineoplastic drugs database
A searchable mirror of National Drug Codes (NDC)
Healthcare Common Procedure Coding Systems (HCPCS) nomenclatures
A glossary of cancer-related terms
Hematopoietic, lymphoid neoplasms and solid tumor diseases
Multiple Primary and Histology Coding Rules
SEER Site-Specific Surgery Codes
Recode algorithms
NAACCR Documentation
Schemas 67
The contract defines 67 schemas that model the data the API accepts and returns. The most detailed are Disease (55 properties), NaaccrItemDto (29 properties), Rx (26 properties), Glossary (21 properties). Each schema is shown below with its type and property counts.
Specification
The full machine-readable OpenAPI contract behind this narrative.
Source
More from Cancer.gov 12
Other APIs Cancer.gov publishes across the network.
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