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NVIDIA NIM

NVIDIA NIM Biology (BioNeMo) API

BioNeMo NIMs for protein structure prediction (AlphaFold2, ESMFold, OpenFold), protein generation (ProtGPT2, RFDiffusion), molecular property prediction (MolMIM), small molecule generation, and molecular docking (DiffDock). Each model is a containerized microservice with the same OpenAPI surface.

Documentation Provider Profile APIs.io OpenAPI GitHub

NVIDIA NIM Biology (BioNeMo) API is one of 10 APIs that NVIDIA NIM publishes on the APIs.io network, described by a machine-readable OpenAPI specification.

Tagged areas include Artificial Intelligence, Biology, BioNeMo, Drug Discovery, and Healthcare. The published artifact set on APIs.io includes API documentation and an OpenAPI specification.

This API exposes 3 operations across 3 paths. It is described by OpenAPI 3.2.0, at version 2026-05-25.

Requests are made against 2 base URLs: https://integrate.api.nvidia.com, http://localhost:8000.

3 operations 3 paths 0 schemas 3 POST

Metadata

The identity and technical contract details declared by the specification.

Specification
OpenAPI 3.2.0
API Version
2026-05-25
Base URL
https://integrate.api.nvidia.com/v1
Authentication
HTTP Bearer
Contact
NVIDIA Developer Support
License
NVIDIA AI Enterprise License
Resource Areas
1

Authentication & Security 1

NVIDIA NIM Biology (BioNeMo) API declares 1 security scheme for authenticating requests. It accepts HTTP bearer tokens (nvapi-...) (BearerAuth). By default, every request must be authenticated.

Paths & Operations 3

Across 3 paths, the API surfaces 3 operations — 3 POST. Each is listed below with its method, path, parameters, and response codes.

Biology 3

Protein, molecule, and structural-biology operations

POST
/v1/biology/nvidia/alphafold2/predict-structure-from-sequence
Predict Protein Structure
predictProteinStructure body → 200400401
POST
/v1/biology/mit/diffdock
Dock Ligand To Protein
dockLigand body → 200400
POST
/v1/biology/nvidia/molmim/generate
Generate Small Molecules
generateMolecules body → 200

Specification

The full machine-readable OpenAPI contract behind this narrative.

Source

nvidia-nim-biology-api-openapi.yml Raw ↑

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#Artificial Intelligence#Biology#BioNeMo#Drug Discovery#Healthcare
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API Details
ID
nvidia-nim:nvidia-nim-biology-api
Base URL
https://integrate.api.nvidia.com/v1
Docs
https://docs.nvidia.com/nim/bionemo/latest/index.html
Provider
NVIDIA NIM
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